Laboratory Resource Center

Immigration Medical Exam
Laboratory Tests Explained

Every USCIS-required lab test — syphilis, gonorrhea, TB blood testing, titer testing, and more — explained in plain language. All testing performed on-site, included in our flat fee.

All labs performed on-site
No fasting required
Results in 1–2 business days
Included in flat fee

Required Laboratory Tests

USCIS mandates a standard laboratory panel for all immigration medical exam applicants. Here is what is required and who needs each test.

Syphilis (RPR)

Required: Age 15+

Rapid Plasma Reagin (RPR) screening test. Reactive results require confirmatory testing (FTA-ABS or TP-PA). Documented in Part 4 of Form I-693.

Method: Blood draw
Results: 1–2 business days

Gonorrhea (NAAT)

Required: All applicants

Nucleic Acid Amplification Test (NAAT) — the most sensitive method for gonorrhea detection. Positive results require treatment before I-693 can be completed.

Method: Urine or swab
Results: 1–2 business days

TB (QuantiFERON-TB Gold)

Required: All applicants

Interferon-Gamma Release Assay (IGRA) — preferred over the tuberculin skin test. A single blood draw; no return visit needed. Positive results require chest X-ray evaluation.

Method: Blood draw (IGRA)
Results: 1–2 business days

All Lab Tests Performed On-Site

No separate lab visits. No extra appointments. All USCIS-required testing is done at our Costa Mesa clinic on the day of your exam — included in the flat fee.

Frequently Asked Questions

Common questions about immigration medical exam laboratory testing.