USCIS Vaccination Requirements for Immigration Medical Exams

Detailed educational guides for every USCIS-required vaccine — including waivers, contraindications, and catch-up schedules.

USCIS-Required Vaccines

Educational guides for each vaccine required by USCIS for immigration medical exams. Requirements vary by age and health history.

MMR

Ages 12 months+ (born 1957 or later)Age-appropriate series

MMR (measles, mumps, rubella) is required for applicants born in 1957 or later, beginning at 12 months of age. Applicants born before 1957 may qualify for presumptive immunity to measles and mumps. Laboratory evidence of immunity may be acceptable for measles, mumps, and rubella.

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Hepatitis B

Generally through age 59Age-appropriate series

Hepatitis B vaccination is generally required through age 59 under the current CDC adjustment-of-status table. Serologic evidence of immunity may be acceptable. The specific series and schedule depend on the applicant's age and vaccination history.

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Varicella

Ages 12 months+Age-appropriate series

Varicella (chickenpox) vaccination is required unless the applicant has documented evidence of prior disease or laboratory evidence of immunity. Laboratory evidence of immunity may be acceptable.

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Tdap / Td

Ages 7+1 Tdap dose + Td every 10 yrs

One lifetime dose of Tdap (tetanus, diphtheria, pertussis) is required for all applicants who have never received it. Td boosters are then required every 10 years. Requirements depend on the applicant's age and documented vaccination history.

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Influenza

Ages 6 months+ (when vaccine available for current season)Annual

Annual influenza vaccination is required for applicants age six months and older when the vaccine is available for the current influenza season. The civil surgeon documents when the influenza vaccine is not available or not flu season.

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Pneumococcal

Ages 2–59 months and ages 65+PCV15/PCV20/PPSV23 per age

Pneumococcal vaccination is required for children from two through 59 months and applicants age 65 and older under the current CDC adjustment-of-status table. The specific vaccine type and schedule depend on age and health status.

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Polio (IPV)

Age-appropriateComplete series per CDC Table 1

Inactivated polio vaccine (IPV) is required according to the applicant's age, documented history, immunity, minimum intervals, and current CDC Table 1. Adults who have never been vaccinated need a primary series.

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HPV

Not currently required for I-693N/A

HPV (human papillomavirus) vaccination is not currently included in the CDC list of vaccines required for adjustment of status. It may be recommended clinically but is not an I-693 requirement.

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Rotavirus

Ages 2–8 months only2 or 3 doses by brand

Rotavirus vaccination is required for infants within the applicable infant age window. The series is brand-specific: Rotarix requires 2 doses; RotaTeq requires 3 doses. The series cannot be started after 15 weeks of age.

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Hib

Ages 2 months–59 months3 or 4 doses by brand

Haemophilus influenzae type b (Hib) vaccination is generally required from ages two months through 59 months. The number of doses depends on the vaccine brand and the child's age at first dose.

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MenACWY

Generally ages 11–18Age-appropriate per CDC Table 1

MenACWY vaccination is generally required from ages 11 through 18 under the current CDC adjustment-of-status table. Requirements depend on the applicant's age, documented history, and current CDC Table 1.

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Hepatitis A

Generally ages 12 months–182 doses (6 months apart)

Hepatitis A vaccination is generally required from 12 months through age 18 under the current CDC adjustment-of-status table. Serologic evidence of immunity (anti-HAV IgG) may be acceptable.

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COVID-19 Vaccination — Not Currently Required

COVID-19 vaccination is not currently required for Form I-693 under the CDC Technical Instructions effective for adjustment-of-status examinations on or after January 20, 2025. Do not list COVID-19 among the current required adjustment-of-status vaccines.

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Vaccine Waivers and Contraindications

The civil surgeon may document blanket-waiver reasons on Form I-693, including: not age appropriate, contraindication, insufficient time interval, and influenza vaccine not available or not flu season. An individual religious or moral waiver is separate — the applicant must request it through USCIS and approval is determined by USCIS, not the civil surgeon. Vaccine refusal is not automatically a medical contraindication.

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Frequently Asked Questions

Common questions about USCIS vaccination requirements for immigration medical exams.

Medical Disclaimer: The information on this page is provided for general educational purposes only and does not constitute medical or legal advice. USCIS vaccination requirements are based on ACIP recommendations and are subject to change. Vaccine requirements vary by age, health history, and current USCIS policy. Always consult a USCIS-designated Civil Surgeon for guidance specific to your case.

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