How Do Multiple Medications Affect the Senior Immigration Medical Exam?

Seniors6 min readUpdated July 2026

How Do Multiple Medications Affect the Senior Immigration Medical Exam?

Quick Answer

Many seniors take multiple medications, and this is a normal part of the immigration medical exam process. Bring a complete and current medication list to your appointment. Certain medications — particularly immunosuppressants — can affect vaccine eligibility and TB test interpretation. Blood thinners require a brief note for the blood draw. You do not need to stop any medications before your exam.

Bring a Complete Medication List to Your Appointment

The single most important thing a senior with multiple medications can do to prepare for the immigration medical exam is to bring a complete and current list of all medications. This list should include prescription medications, over-the-counter medications, vitamins, supplements, and herbal remedies. For each medication, include the name, dosage, and how often you take it.

The civil surgeon will review your medication list as part of the medical history portion of the exam. This review helps the civil surgeon understand your overall health status, identify any conditions that may affect the exam process, and determine whether any medications have implications for vaccine administration or test interpretation.

If you take many medications, consider printing a list from your pharmacy or asking your primary care physician to provide a current medication reconciliation. Many pharmacies can print a complete medication history upon request. Bringing the actual medication bottles is also acceptable, though a printed list is easier to review quickly.

How Medications Affect Vaccine Eligibility

Certain medications can affect which vaccines you are eligible to receive at the time of your immigration medical exam. The most important category is immunosuppressive medications, which include corticosteroids (such as prednisone), disease-modifying antirheumatic drugs (DMARDs such as methotrexate), biologic agents (such as TNF inhibitors like adalimumab or etanercept), and medications used after organ transplant.

Immunosuppressive medications are a contraindication for live vaccines. Live vaccines used in the immigration medical exam context include the MMR (measles, mumps, rubella) vaccine and the varicella (chickenpox) vaccine. If you are on immunosuppressive therapy, the civil surgeon will not administer live vaccines while you are actively immunosuppressed. Instead, the civil surgeon will document the contraindication on Form I-693 and may defer those vaccines until your immune status changes.

Non-live (inactivated) vaccines — including influenza, pneumococcal, Tdap, and shingles (Shingrix) — are generally safe to administer even in immunosuppressed patients, though their effectiveness may be reduced. The civil surgeon will administer these vaccines as indicated by the ACIP schedule unless there is a specific medical contraindication.

Immunosuppressants and the TB Test

Immunosuppressive medications can also affect the accuracy of TB testing. Both the tuberculin skin test (TST) and the interferon-gamma release assay (IGRA) rely on the immune system's response to TB antigens. Immunosuppression can blunt this response, leading to false-negative results — meaning the test may appear negative even if TB infection is present.

If you are on immunosuppressive medications, the civil surgeon will take this into account when interpreting your TB test results. In some cases, the civil surgeon may rely more heavily on the chest X-ray findings or may consult with your treating physician. It is important to disclose all immunosuppressive medications at your appointment so that the civil surgeon can interpret your results accurately.

Do not stop immunosuppressive medications before your immigration medical exam without consulting your treating physician. Stopping these medications can have serious health consequences and is not required or recommended for the immigration exam.

Blood Thinners and the Blood Draw

Some seniors take anticoagulant or antiplatelet medications — commonly called blood thinners — such as warfarin (Coumadin), apixaban (Eliquis), rivaroxaban (Xarelto), clopidogrel (Plavix), or aspirin. These medications do not prevent you from having a blood draw, but they do increase the risk of bruising at the venipuncture site.

Inform the civil surgeon or the phlebotomist that you are on a blood thinner before the blood draw. Our staff will apply firm pressure to the site after the draw and will monitor for any excessive bleeding. In most cases, the blood draw proceeds without any complications. You do not need to stop blood thinners before your immigration medical exam.

If you are on warfarin and have a recent INR result, you may bring it to your appointment, though it is not required. The civil surgeon does not need to review your INR for the purposes of the immigration medical exam.

What the Civil Surgeon Reviews Regarding Medications

The civil surgeon will review your medication list to understand your overall health status and to identify any conditions that may be relevant to the immigration medical exam. The civil surgeon is not evaluating whether your medications are appropriate or whether your conditions are well-managed — that is the role of your treating physician. Rather, the civil surgeon is looking for information that is relevant to the specific requirements of the immigration medical exam.

Relevant considerations include: whether any medications indicate the presence of a communicable disease (such as HIV antiretrovirals or TB medications), whether any medications are contraindications for required vaccines, and whether any medications affect the interpretation of required tests such as the TB test.

The civil surgeon will document relevant medication information on Form I-693 as appropriate. In most cases, medications for common chronic conditions such as hypertension, diabetes, high cholesterol, or arthritis do not have any specific implications for the immigration medical exam and will simply be noted as part of the medical history.

No Need to Stop Medications Before the Exam

A common concern among seniors with multiple medications is whether they need to stop or adjust any medications before the immigration medical exam. In virtually all cases, the answer is no. You should continue taking all of your medications as prescribed and should not make any changes to your medication regimen in preparation for the exam.

The only exception would be if your treating physician specifically advises a medication change for an unrelated medical reason. If your physician has recommended a medication change, follow their advice and inform the civil surgeon of any recent changes at your appointment.

Taking your medications as usual on the day of your exam is important for your health and safety. If you have any questions about specific medications and the immigration medical exam, you are welcome to call our clinic in advance to speak with our staff.

Frequently Asked Questions

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