Legal Basis for Syphilis Testing

Under the Immigration and Nationality Act (INA), USCIS requires screening for communicable diseases of public health significance as part of the immigration medical examination. Syphilis — particularly in its infectious stages — falls within this category. The Centers for Disease Control and Prevention (CDC) and USCIS have established that all applicants aged 15 and older must be tested for syphilis using a serologic blood test.

What the Test Involves

Syphilis testing is performed via a blood draw. The standard approach uses a two-step serologic process: a non-treponemal screening test (such as RPR) followed by a confirmatory treponemal test if the initial result is reactive. Both tests are performed on-site at our clinic, and results are typically available within 1 to 2 business days.

What Happens If the Result Is Positive

A reactive syphilis test does not automatically prevent you from obtaining a green card. The civil surgeon will evaluate the stage of infection and whether treatment has been completed. Treated syphilis with documented cure is generally not a ground of inadmissibility.

If active syphilis is identified, treatment will be required before Form I-693 can be completed. Our civil surgeon will discuss your options and refer you to appropriate care if needed.

Who Is Exempt From Syphilis Testing

Applicants under 15 years of age are not required to undergo syphilis testing as part of the standard immigration medical examination. All other applicants — regardless of gender, marital status, or country of origin — are required to be tested.